Ethical implications of research

Are going through a time of profound change in our understanding of the ethics d social research. There was a gradually developing consensus about the key ethical principles underlie the research endeavor. Cancer patients and persons fought publicly with the medical research establishment about the long time needed approval for and complete research into potential cures for fatal diseases. But now, those who were threatened illness were saying to the research establishment that they wanted to be ts, even under experimental conditions of considerable risk. You had several and articulate patient groups who wanted to be experimented on coming up against l review system that was designed to protect them from being experimented gh the last few years in the ethics of research have been tumultuous ones, it ing to appear that a new consensus is evolving that involves the stakeholder affected by a problem participating more actively in the formulation of research. Allowing anyone who is willing to be are a number of key phrases that describe the system of ethical protections contemporary social and medical research establishment have created to try to the rights of their research participants. The principle of ipation requires that people not be coerced into participating in is especially relevant where researchers had previously relied on 'captive audiences'. Closely related to of voluntary participation is the requirement of informed ially, this means that prospective research participants must be fully the procedures and risks involved in research and must give their consent ipate. Ethical standards also require that researchers not put participants in ion where they might be at risk of harm as a result of ipation. There are rds that are applied in order to help protect the privacy of research all research guarantees the participants confidentiality -- they d that identifying information will not be made available to anyone who is ly involved in the study. Increasingly, researchers have had to deal with the ethical issue of 's right to service. But when that treatment or program may cial effects, persons assigned to the no-treatment control may feel their rights access to services are being when clear ethical standards and principles exist, there will be times when to do accurate research runs up against the rights of potential participants. Furthermore, there be a procedure that assures that researchers will consider all relevant ethical formulating research plans. To address such needs most institutions and formulated an institutional review board (irb), a panel of persons s grant proposals with respect to ethical implications and decides onal actions need to be taken to assure the safety and rights of participants. Ing proposals for research, irbs also help to protect both the organization and cher against potential legal implications of neglecting to address important of ght 2006, william m. Trochim, all rights se a printed copy of the research methods revised: 10/20/ble of contentsnavigatingfoundationslanguage of researchphilosophy of researchethics in researchconceptualizingevaluation re skillsyouneed:A - z list of learning skills. Types of learning tanding your preferences to aid al thinking al thinking and fake g a dissertation or to write a research l issues in tation: the ching and writing a literature g your tation: results and tation: conclusions and g your dissertation or thesis of the skills you need guide for ng, coaching, mentoring and ability skills for ibe to our free newsletter and start improving your life in just 5 minutes a 'll get our 5 free 'one minute life skills' and our weekly 'll never share your email address and you can unsubscribe at any l issues in also: writing a research are broadly the set of rules, written and unwritten, that govern our expectations of our own and others’ behaviour. While there is broad agreement on some ethical values (for example, that murder is bad), there is also wide variation on how exactly these values should be interpreted in ch ethics are the set of ethics that govern how scientific and other research is performed at research institutions such as universities, and how it is page explains more about research ethics, and how you can ensure that your research is are research ethics? Most people think of research ethics, they think about issues that arise when research involves human or animal these issues are indeed a key part of research ethics, there are also wider issues about standards of conduct. These include the importance of publishing findings in a transparent way, not plagiarising others’ work, and not falsifying importance of research ch ethics are important for a number of promote the aims of research, such as expanding support the values required for collaborative work, such as mutual respect and fairness. This is essential because scientific research depends on collaboration between researchers and mean that researchers can be held accountable for their actions. Many researchers are supported by public money, and regulations on conflicts of interest, misconduct, and research involving humans or animals are necessary to ensure that money is spent ensure that the public can trust research. For people to support and fund research, they have to be confident in support important social and moral values, such as the principle of doing no harm to : resnick, d. Agencies who fund or commission research often publish codes of conduct for researchers, or codes of example, the us national institutes of health (nih) and food and drug administration (fda) both publish ethical codes. Some ethical codes may have the force of law behind them, while others may simply be aware that even if you do nothing illegal, doing something unethical may end your research or even most ethical codes cover the following areas:Honesty and means that you need to report your research honestly, and that this applies to your methods (what you did), your data, your results, and whether you have previously published any of it. It is better to undersell than over-exaggerate your working with others, you should always keep to any agreements, and act should aim to avoid bias in any aspect of your research, including design, data analysis, interpretation, and peer review. For example, you should never recommend as a peer reviewer someone you know, or who you have worked with, and you should try to ensure that no groups are inadvertently excluded from your research. This also means that you need to disclose any personal or financial interests that may affect your care in carrying out your research to avoid careless mistakes. Obviously, you need to respect copyrights and patents, together with other forms of intellectual property, and always acknowledge contributions to your research. You should also follow guidelines on protection of sensitive information such as patient sible should publish to advance to state of research and knowledge, and not just to advance your career. This means, in essence, that you should not publish anything that is not new, or that duplicates someone else’s should always be aware of laws and regulations that govern your work, and be sure that you conform to you are using animals in your research, you should always be sure that your experiments are both necessary and well-designed. You should also show respect for the animals you are using, and make sure that they are properly cared subjects your research involves people, you should make sure that you reduce any possible harm to the minimum, and maximise the benefits both to participants and other means, for example, that you should not expose people to more tests than are strictly necessary to fulfil your research aims. This is required to scrutinise all research proposals, to ensure that they do not raise any ethical issues.

Ethical implications of psychological research

This will generally include research for master’s and undergraduate degrees, although undergraduate research may be covered by a broader research proposal from your is likely to be a standard form to complete for ethical approval, which will cover who will be involved, how you will recruit your participants, and what steps you will take to ensure that they have provided informed is an example form on our page writing a research proposal, which also contains more detail about how to go about preparing a ethics committee’s role is to consider that what you are doing is appropriate and proportionate to your research a research proposal raises ethical issues, the committee will ask the researcher to look again at the issue, and consider whether they could do it example, if you are proposing to carry out a study on a particular disease, and you want to ask all your participants whether they are married and have any children, the committee may want to know why this is relevant. It may be relevant (for example, if you think the disease may be reduced by living in a family), in which case, you will need to justify committee may also suggest alternative methods that they think are more suitable for the target group, or additional precautions that you should cannot start your research until you have been granted ethical approval, which will be granted formally, together with an approval you publish your research, whether as a thesis or in one or more journal articles, you will need to provide details of the ethical approval, including this you are unsure how to behave in a particular situation…. And think you may have an ethical dilemma, then you should always seek advice before you you are a student, your supervisor should be happy to help and advise you. If necessary, they will be able to advise you about who else to a researcher, you should consult more senior colleagues around, either at your own institution or others, who should be happy to help all, it is in everyone’s interests to promote research ethics, and support the integrity and reputation of g a g a literature review | academic ng styles | sources of @ might be the ethical issues and risks that arise in my research? University of are some examples of what might be an ethical issue or risk in research. This is not an exhaustive list – you may identify other issues in your own research project. Are my own students or ipants are an over-researched ipants do not understand english / might not adequately understand verbal explanations or written information / have low functional s around is a conflict of interest for the s around recruitment of ipants may be approached in a public ipation is not voluntary, or there is coercion or incentive to cher or faculty / department / university has a financial interest in the participant may not be able to withdraw from the ion is nature of the ipants may disclose that they have broken the or hazards to participants or al or mental risk or or pain / distress / discomfort to the participant or of samples e. Back to guidance on ethical approval for research main the browser controls to adjust the font size, or print this is ethics in research & why is it important? This is the most common way of defining "ethics": norms for conduct that distinguish between acceptable and unacceptable people learn ethical norms at home, at school, in church, or in other social settings. Ethical norms are so ubiquitous that one might be tempted to regard them as simple commonsense. On the other hand, if morality were nothing more than commonsense, then why are there so many ethical disputes and issues in our society? Plausible explanation of these disagreements is that all people recognize some common ethical norms but interpret, apply, and balance them in different ways in light of their own values and life experiences. For example, two people could agree that murder is wrong but disagree about the morality of abortion because they have different understandings of what it means to be a human societies also have legal rules that govern behavior, but ethical norms tend to be broader and more informal than laws. Although most societies use laws to enforce widely accepted moral standards and ethical and legal rules use similar concepts, ethics and law are not the same. We can also use ethical concepts and principles to criticize, evaluate, propose, or interpret laws. Peaceful civil disobedience is an ethical way of protesting laws or expressing political r way of defining 'ethics' focuses on the disciplines that study standards of conduct, such as philosophy, theology, law, psychology, or sociology. For instance, in considering a complex issue like global warming, one may take an economic, ecological, political, or ethical perspective on the problem. While an economist might examine the cost and benefits of various policies related to global warming, an environmental ethicist could examine the ethical values and principles at different disciplines, institutions, and professions have standards for behavior that suit their particular aims and goals. Ethical norms also serve the aims or goals of research and apply to people who conduct scientific research or other scholarly or creative activities. See glossary of commonly used terms in research are several reasons why it is important to adhere to ethical norms in research. First, norms promote the aims of research, such as knowledge, truth, and avoidance of error. For example, prohibitions against fabricating, falsifying, or misrepresenting research data promote the truth and minimize , since research often involves a great deal of cooperation and coordination among many different people in different disciplines and institutions, ethical standards promote the values that are essential to collaborative work, such as trust, accountability, mutual respect, and fairness. For example, many ethical norms in research, such as guidelines for authorship, copyright and patenting policies, data sharing policies, and confidentiality rules in peer review, are designed to protect intellectual property interests while encouraging collaboration. Most researchers want to receive credit for their contributions and do not want to have their ideas stolen or disclosed , many of the ethical norms help to ensure that researchers can be held accountable to the public. For instance, federal policies on research misconduct, conflicts of interest, the human subjects protections, and animal care and use are necessary in order to make sure that researchers who are funded by public money can be held accountable to the , ethical norms in research also help to build public support for research. People are more likely to fund a research project if they can trust the quality and integrity of y, many of the norms of research promote a variety of other important moral and social values, such as social responsibility, human rights, animal welfare, compliance with the law, and public health and safety. Ethical lapses in research can significantly harm human and animal subjects, students, and the public. For example, a researcher who fabricates data in a clinical trial may harm or even kill patients, and a researcher who fails to abide by regulations and guidelines relating to radiation or biological safety may jeopardize his health and safety or the health and safety of staff and and policies for research the importance of ethics for the conduct of research, it should come as no surprise that many different professional associations, government agencies, and universities have adopted specific codes, rules, and policies relating to research ethics. Many government agencies, such as the national institutes of health (nih), the national science foundation (nsf), the food and drug administration (fda), the environmental protection agency (epa), and the us department of agriculture (usda) have ethics rules for funded researchers. Other influential research ethics policies include singapore statement on research integrity, the american chemical society, the chemist professional’s code of conduct, code of ethics (american society for clinical laboratory science) american psychological association, ethical principles of psychologists and code of conduct, statements on ethics and professional responsibility (american anthropological association), statement on professional ethics (american association of university professors), the nuremberg code and the world medical association's declaration of following is a rough and general summary of some ethical principals that various codes address*:Strive for honesty in all scientific communications. Do not deceive colleagues, research sponsors, or the to avoid bias in experimental design, data analysis, data interpretation, peer review, personnel decisions, grant writing, expert testimony, and other aspects of research where objectivity is expected or required. Keep good records of research activities, such as data collection, research design, and correspondence with agencies or data, results, ideas, tools, resources. Never t confidential communications, such as papers or grants submitted for publication, personnel records, trade or military secrets, and patient sible h in order to advance research and scholarship, not to advance just your own career.

Promote their welfare and allow them to make their own t for t your colleagues and treat them to promote social good and prevent or mitigate social harms through research, public education, and discrimination against colleagues or students on the basis of sex, race, ethnicity, or other factors not related to scientific competence and in and improve your own professional competence and expertise through lifelong education and learning; take steps to promote competence in science as a and obey relevant laws and institutional and governmental proper respect and care for animals when using them in research. Do not conduct unnecessary or poorly designed animal subjects conducting research on human subjects, minimize harms and risks and maximize benefits; respect human dignity, privacy, and autonomy; take special precautions with vulnerable populations; and strive to distribute the benefits and burdens of research fairly. It is therefore important for researchers to learn how to interpret, assess, and apply various research rules and how to make decisions and to act ethically in various situations. For example, consider the following case,The research protocol for a study of a drug on hypertension requires the administration of the drug at different doses to 50 laboratory mice, with chemical and behavioral tests to determine toxic effects. He therefore decides to extrapolate from the 45 completed results to produce the 5 additional different research ethics policies would hold that tom has acted unethically by fabricating data. If this study were sponsored by a federal agency, such as the nih, his actions would constitute a form of research misconduct, which the government defines as "fabrication, falsification, or plagiarism" (or ffp). It is important to remember, however, that misconduct occurs only when researchers intend to deceive: honest errors related to sloppiness, poor record keeping, miscalculations, bias, self-deception, and even negligence do not constitute misconduct. The error does not affect the overall results of his research, but it is potentially misleading. Failing to publish a correction would be unethical because it would violate norms relating to honesty and objectivity in are many other activities that the government does not define as "misconduct" but which are still regarded by most researchers as unethical. These are sometimes referred to as "other deviations" from acceptable research practices and include:Publishing the same paper in two different journals without telling the ting the same paper to different journals without telling the informing a collaborator of your intent to file a patent in order to make sure that you are the sole ing a colleague as an author on a paper in return for a favor even though the colleague did not make a serious contribution to the sing with your colleagues confidential data from a paper that you are reviewing for a data, ideas, or methods you learn about while reviewing a grant or a papers without ng outliers from a data set without discussing your reasons in an inappropriate statistical technique in order to enhance the significance of your ing the peer review process and announcing your results through a press conference without giving peers adequate information to review your ting a review of the literature that fails to acknowledge the contributions of other people in the field or relevant prior hing the truth on a grant application in order to convince reviewers that your project will make a significant contribution to the hing the truth on a job application or curriculum the same research project to two graduate students in order to see who can do it the rking, neglecting, or exploiting graduate or post-doctoral g to keep good research g to maintain research data for a reasonable period of derogatory comments and personal attacks in your review of author's ing a student a better grade for sexual a racist epithet in the significant deviations from the research protocol approved by your institution's animal care and use committee or institutional review board for human subjects research without telling the committee or the reporting an adverse event in a human research g animals in ng students and staff to biological risks in violation of your institution's biosafety ging someone's ng supplies, books, or g an experiment so you know how it will turn unauthorized copies of data, papers, or computer over $10,000 in stock in a company that sponsors your research and not disclosing this financial rately overestimating the clinical significance of a new drug in order to obtain economic actions would be regarded as unethical by most scientists and some might even be illegal in some cases. However, they do not fall into the narrow category of actions that the government classifies as research misconduct. Indeed, there has been considerable debate about the definition of "research misconduct" and many researchers and policy makers are not satisfied with the government's narrow definition that focuses on ffp. However, given the huge list of potential offenses that might fall into the category "other serious deviations," and the practical problems with defining and policing these other deviations, it is understandable why government officials have chosen to limit their y, situations frequently arise in research in which different people disagree about the proper course of action and there is no broad consensus about what should be done. In these situations, there may be good arguments on both sides of the issue and different ethical principles may conflict. She receives a request from another research team that wants access to her complete dataset. On the one hand, the ethical norm of openness obliges her to share data with the other research team. Another option would be to offer to collaborate with the following are some step that researchers, such as dr. Wexford, can take to deal with ethical dilemmas in research:What is the problem or issue? In this case, the issue is whether to share information with the other research is the relevant information? In this case, there may be other choices besides 'share' or 'don't share,' such as 'negotiate an agreement' or 'offer to collaborate with the researchers. Do ethical codes or policies as well as legal rules apply to these different options? Broader ethical rules, such as openness and respect for credit and intellectual property, may also apply to this case. Laws relating to intellectual property may be there any people who can offer ethical advice? May be useful to seek advice from a colleague, a senior researcher, your department chair, an ethics or compliance officer, or anyone else you can trust. Wexford might want to talk to her supervisor and research team before making a considering these questions, a person facing an ethical dilemma may decide to ask more questions, gather more information, explore different options, or consider other ethical rules. Ideally, a person who makes a decision in an ethical dilemma should be able to justify his or her decision to himself or herself, as well as colleagues, administrators, and other people who might be affected by the decision. Endorsing these methods in this context need not imply that ethical decisions are irrational, however. The main point is that human reasoning plays a pivotal role in ethical decision-making but there are limits to its ability to solve all ethical dilemmas in a finite amount of ing ethical conduct in academic institutions in the us require undergraduate, graduate, or postgraduate students to have some education in the responsible conduct of research (rcr). The nih and nsf have both mandated training in research ethics for students and trainees. Many academic institutions outside of the us have also developed educational curricula in research of you who are taking or have taken courses in research ethics may be wondering why you are required to have education in research ethics. You may believe that you are highly ethical and know the difference between right and wrong. Indeed, you also may believe that most of your colleagues are highly ethical and that there is no ethics problem in research.. Indeed, the evidence produced so far shows that misconduct is a very rare occurrence in research, although there is considerable variation among various estimates.

Of researchers per year (based on confirmed cases of misconduct in federally funded research) to as high as 1% of researchers per year (based on self-reports of misconduct on anonymous surveys). See shamoo and resnik (2015), cited y, it would be useful to have more data on this topic, but so far there is no evidence that science has become ethically corrupt, despite some highly publicized scandals. Even if misconduct is only a rare occurrence, it can still have a tremendous impact on science and society because it can compromise the integrity of research, erode the public’s trust in science, and waste time and resources. In any case, a course in research ethics will have little impact on "bad apples," one might ing to the "stressful" or "imperfect" environment theory, misconduct occurs because various institutional pressures, incentives, and constraints encourage people to commit misconduct, such as pressures to publish or obtain grants or contracts, career ambitions, the pursuit of profit or fame, poor supervision of students and trainees, and poor oversight of researchers (see shamoo and resnik 2015). In any case, a course in research ethics can be useful in helping to prevent deviations from norms even if it does not prevent misconduct. Education in research ethics is can help people get a better understanding of ethical standards, policies, and issues and improve ethical judgment and decision making. Many of the deviations that occur in research may occur because researchers simply do not know or have never thought seriously about some of the ethical norms of research. For example, some unethical authorship practices probably reflect traditions and practices that have not been questioned seriously until recently. Another example where there may be some ignorance or mistaken traditions is conflicts of interest in research. A researcher may think that a "normal" or "traditional" financial relationship, such as accepting stock or a consulting fee from a drug company that sponsors her research, raises no serious ethical issues. Or perhaps a university administrator sees no ethical problem in taking a large gift with strings attached from a pharmaceutical company. Maybe a physician thinks that it is perfectly appropriate to receive a $300 finder’s fee for referring patients into a clinical "deviations" from ethical conduct occur in research as a result of ignorance or a failure to reflect critically on problematic traditions, then a course in research ethics may help reduce the rate of serious deviations by improving the researcher's understanding of ethics and by sensitizing him or her to the y, education in research ethics should be able to help researchers grapple with the ethical dilemmas they are likely to encounter by introducing them to important concepts, tools, principles, and methods that can be useful in resolving these dilemmas. Scientists must deal with a number of different controversial topics, such as human embryonic stem cell research, cloning, genetic engineering, and research involving animal or human subjects, which require ethical reflection and b. Mail: mantzorou@ for more related articles at health science ound: research ethics involve requirements on daily work, the protection of dignity of subjects and the publication of the information in the research. However, when nurses participate in research they have to cope with three value systems; society; nursing and science which may be in conflict with the values of subjects, communities, and societies and create tensions and dilemmas in nursing. Method and material: using the medline and the nursing cinahl data base, the most important ethical issues which appear in bibliography, will be addressed. After a short description of the nature of nursing, and the advocacy role of nurses, the writer will attempt to highlight the possible conflicts that nurses have to deal with, when undertaking or participating in research. Results: the major ethical issues in conducting research are: a) informed consent, b) beneficence- do not harm c) respect for anonymity and confidentiality d) respect for privacy. However, both the nature of nursing which focuses on caring, preventing harm and protecting dignity and the advocates role of nurses which calls for defending the rights of subjects, are sometimes incongruent with the ethics in research. Conclusions: ethical issues, conflicting values, and ambiguity in decision making, are recurrently emerging from literature review on nursing research. Because of lack of clarity in ethical standards, nurses must develop an awareness of these issues and an effective framework to deal with problems involving human ch ethics, moral dilemmas in research, nature of nursing, nursing research, nursing is rooted in the ancient greek philosophical inquiry of moral life. Scientific research work, as all human activities, is governed by individual, community and social values. Research ethics involve requirements on daily work, the protection of dignity of subjects and the publication of the information in the r, when nurses participate in research they have to cope with three value systems; society; nursing and science. The societal values about human rights, the nursing culture based on the ethic of caring and the researcher's values about scientific inquiry. After a short description of the nature of nursing, and the advocacy role of nurses, the writer will attempt to highlight the possible conflicts that nurses have to deal with, when undertaking or participating in ical overview- ethical experimentation has been conducted even before 18th century. However, the ethical attitudes of researchers drawn the interest of society only after 1940's because of human exploitation in several cases. 4] the nazi experiments led to the nuremberg code (1947) which was the leading code for all subsequent codes made to protect human rights in research. This code focuses on voluntary informed consent, liberty of withdrawal from research, protection from physical and mental harm, or suffering and death. 5] the only weak point of this code was the self regulation of researchers which can be abused in some research studies. It was only in 1964 with the declaration of helsinki that the need for non therapeutic research was initiated. 6] the declaration emphasised the protection of subjects in this kind of research and strongly proclaimed that the well being of individuals is more important than scientific and social interests. Since then there has been a significant development of professional codes in conduct and research. The american nurses' association (ana) guidelines for research, the human rights guidelines for nurses in clinical and other research (1985) and the royal college of nursing code for nurses in research (1977) provide a strong assistance to professional nurses as well as reassurance to patients, the public and society, of professionals’ intentions.

3] of course individuals can make informed decisions in order to participate in research voluntarily only if they have information on the possible risks and benefits of the research. 12] free and informed consent needs to incorporate an introduction to the study and its purpose as well as an explanation about the selection of the research subjects and the procedures that will be followed. 13] the researcher must inform the subjects about the methods which will be used to protect anonymity and confidentiality and indicate a person with whom they can discuss the study. The researcher must also take into account that persons with physical, cultural and emotional barriers may require a very simple language in order to understand him. 5] this is very important but raises the issue of how difficult the subjects can withdraw after developing a personal and sometimes friendly relationship with the researcher. 12] with regard to withdrawal a researcher may be in a dilemma in case many subjects choose to withdraw at an advanced stage of the study, because this can affect the validity of the results. 3] according to this, the will of the subject must be respected at any cost for the r major ethical issue is obtaining an informed consent from groups with diminished autonomy which will be further discussed later. Do not ethical principle of beneficence refers to the hippocratic "be of benefit, do not harm". The principle of beneficence includes the professional mandate to do effective and significant research so as to better serve and promote the welfare of our constituents". Carr says that if the research findings prove that it was not beneficial as it s expected, this can raise immense ethical considerations especially for nurses. 16] ford and reutter say that "beneficence relates to the benefits of the research, while non-malificence relates to the potential risks of participation". A researcher tries to learn intimate details of the participants lives he has to deal with opening old wounds. A researcher must consider all possible consequences of the research and balance the risks with proportionate benefit. If the researcher is not able to promise anonymity he has to address confidentiality, which is the management of private information by the researcher in order to protect the subject's identity. Clarke addresses the ethical dilemma of the researcher when confidentiality must be broken because of the moral duty to protect society. If a researcher, though, acts deontologically he may feel that he has not protected society. Another issue is that the researcher may have to report confidential information to courts which can also dilemmas. 3] even if there are no duty conflicts, the researcher faces several problems with respect to maintaining confidentiality especially in qualitative research where conduct is personal, the sample is smaller and the reports display quotations of interviews. Department of health and human services (dhhs) may be useful to help ensure the privacy of research participants especially in studies in which participants and researchers may be exposed to compelled legal disclosure of research researchers must always bear in mind all psychological and social implications that a breach of confidentiality may have on subjects. All aims, instruments and methodology must be discussed with the prospective subject and the research workers prior to the and treece suggest that whenever subjects refuse to report personal information as they regard it an invasion of privacy, the researcher ought to respect their views. They also imply that privacy can be invaded when researchers study certain groups without their knowledge and without identifying themselves. An example of such a study that the researcher hid his identity, was humphrie's study "impersonal sex in public places" in which, he observed homosexuals during sexual activities in public men's rooms. 5] in conclusion, all possible measures have to be taken in order to protect subjects from potential physical, psychological or social damage during the research or after circulation of the results. Groups of ys, there is an increased concern about vulnerable groups and whether it is ethical or not for them to be used as research subjects. 23] so, vulnerable groups include captive populations (prisoners, institutionalised, students etc), mentally ill persons, aged people, children, critically ill or dying, poor, with learning disabilities, sedated or different opinions about their participation in research can be attributed to their inability to give an informed consent and also to their need for further protection and sensitivity from the researcher as they are in a greater risk of being deceived, threatened or forced to participate. Many are in favour of the use of such subjects in research whilst others would argue strongly against it. Most condition their responses according to the seriousness of the research, the level of potential risk and the availability of alternatives. An intense analysis of potential risks and benefits should be the first step of starting such a research and careful approach should exist both in acquiring consent and during the research procedure itself. In the case of mentally ill patients, it is important to measure comprehension and develop valid tools for it, before obtaining informed consent to participate in a research study. 25] however, the potential improvement of their nursing care raises the issue of careful consideration before rejecting or accepting this kind of of the n declares that in research the three more important elements are the competency of the researcher, the careful design, and worthwhile expected outcomes. 13] the royal college of nurses declares that nurse researchers should have the necessary skills and knowledge for the specific investigation to be carried out and be aware of the limits of personal competence in research. Inexperienced researchers should work under qualified supervision which has to be reviewed by an ethics committee. Is more, careful choice of method for data collection, to ensure validity and reliability, are two main requirements that must be met in all kinds of research.

When human beings are involved, all the ethical issues, discussed above, must be taken into account. Common feature in professional conduct codes and those specific to research is the principle of non-malificence. The ana code of conduct declares that the nurse protects the clients and the public from unethical, incompetent or illegal practice of any person. 8] this statement raises the issue of advocacy when nurses have to protect patients from the researchers’ incompetence or unethical behaviour. 13] if the researcher does not inform or compensate patient then nurses have to decide between the duty to safeguard the well-being of patient and be loyal to them, and the loyalty to r, even if nurses decide that their duty of caring and being loyal to the patient is more important, they may have to deal with the hierarchical and bureaucratic systems of institutions which demand loyalty to subordinates to the institution. In case the incompetent researcher is a higher status professional, nurses may be obliged to show loyalty, but this can conflict with loyalty to patients. This is merely why many authors believe that it may not be possible for nurses to act as advocates of subjects in research. Possible issue of conflict is that the caring nature of nursing with regard to the right of patients to the best treatment/care is sometimes conflicting with the aim of research in non therapeutic studies. According to the belmond commission the general aim of practice is to enhance the well being of individuals while the purpose of research is to contribute to general knowledge. This distinction highlights the differences in the aims of a nurse practitioner and a researcher. 43] clark warns that there is a danger that the members may have vested interests in a research. If instead of the patient and his needs, the central aims of the committee are personal interests, profits and academic prestige, then nurses will have none to share their concerns with, and deal with their dilemmas in research. 26] moreover, the committees should be less strict so as not to prevent knowledge development in issue of confidentiality which is stated as very important in the hippocratic oath, is another possible issue of conflict for nurses either as practitioners or researchers. 9] on the other hand the icn code for nurses in research states that: "nurses acting as data collectors must recognise that they are now committed to two separate roles " . To the professional code they can not reveal confidential information not even to the members of the research team. 26] in addition, they have to deal with the issue of anonymity when some features of the research make the subjects easy to identify. Involved in research, have to consider many ethical problems relating to the issue of informed consent. The icn code for nurses in research, states that nurses as practitioners may be called upon to witness that informed and voluntary consent has been obtained from the subjects of research. Webb suggests that the informed consent is an obligation of the researcher and no nurse should obtain it on behalf of another professional, nor agree to give the explanation as a substitute. Conflicting issue is that giving information to patients is accepted as a major role of the nurse; but if for the sake of a research, nurses have to withhold information, this may create conflicts when they have to decide whether to participate or not. 40] hurst suggests that if nurses cannot tell patients about the true research objectives, they should provide a full explanation at the end of data collection. 45] provided, of course, that a supervisor body has decided that disclosure should not be full in order not to invalidate the research t, can however, be a major ethical issue for nurses when it involves persons with diminished autonomy, such as children, aged, mentally ill etc. Nurses taking part in research on children should be alert, in order to notice any verbal or non verbal dissent which warrants exclusion of the child from the study (even if this creates conflicts with the researcher. 46] in the same prospect, nurses must act as advocates when vulnerable groups are used in research, and not prevent it. According to levine, restricting these groups from research could end in disadvantaging those populations, even further, especially when research involves no risk and a high potential for benefit. Role regard to nurse researchers, the international council of nurses declares that they are not responsible for the care of patients. 3] the commitment of nurses to caring, may create dilemmas according to the conflict between the researcher's and clinician's a researcher nurse provides physical or psychological care during an interview, the results will be biased and generalisation will be difficult. 5] another issue raised from the icn statement, is to determine when a "harmful situation appears imminent" and the intervention of the researcher is required. 3] this can solve some of the ethical dilemmas of the nurse, but in case the situation is not lifethreatening, the conflict remains. Burns and grove suggest that in case that support from the researcher is required, then, it should be given, but the subjects should be excluded from the research. Nevertheless, most health professionals, no matter how skilled they are in supportive techniques will provide some care if they feel that it is needed in a certain l issues, conflicting values, and ambiguity in decision making, are recurrently emerging from literature review on nursing research. Because of lack of clarity in ethical standards, nurses must develop an awareness of these issues and an effective framework to deal with problems involving human rights. This is necessary in order to come into terms with the issue of the researcher's values relative to the individual's rights versus the interests of society.

Professional codes, laws, regulations, and ethics committees can provide some guidance but the final determinant of how research is performed, rests with the researcher's value system and moral code. He also declares that nursing, not as a biomedical branch, but as a science and art of caring, is able to start the redefinition of research in health care which was in the recent history dominated by the biomedical "paradigm". Nursing research,1982;(1): 43- college of nursing, ethics related to research in nursing, london,d p.