Research paper on leukemia

Impact factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. Sjr uses a similar algorithm as the google page rank; it provides a quantitative and a qualitative measure of the journal’s more on journal example article on lides are short, 5-minute presentations in which the author explains their paper in their own application allows readers to interactively explore high-resolution slide images using a "virtual microscope". This free service is available to anyone who has published and whose publication is in practice & research: clinical y of blood and marrow al lymphoma, myeloma & mental logy/oncology clinics of north ia research rs in ia research is an international journal which brings comprehensive and current information to all health care professionals involved in basic and (or) applied clinical research in leukemias, lymphomas, multiple myeloma and other hematologic malignancies. Research is an international journal which brings comprehensive and current information to all health care professionals involved in basic and (or) applied clinical research in leukemias, lymphomas, multiple myeloma and other hematologic malignancies. Specifically, of major interest will be articles that encompass the application of oncogenes, growth factors, cell markers, cell cycle and differentiation agents, novel therapeutics and clinical trials in both the acute and chronic leukemias as well as the myelodysplastic syndromes. Phase 1/2 study of rigosertib in patients with myelodysplastic syndromes (mds) and mds progressed to acute myeloid leukemia. Nathalie ed survival in mds patients receiving iron chelation therapy - a matched pair analysis of 188 patients from the düsseldorf mds s repositioning of quinacrine for treatment of acute myeloid leukemia – promising synergies and in vivo -dose lenalidomide plus cytarabine in very elderly, unfit acute myeloid leukemia patients: final result of a phase ii treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion downloaded most downloaded articles from leukemia research in the last 90 proliferative disease and cancer among patients with common variable advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (mds). In adult acute ly published articles from leukemia chelation therapy in lower ipss risk myelodysplastic syndromes; which subtypes benefit? Nathalie ed survival in mds patients receiving iron chelation therapy - a matched pair analysis of 188 patients from the düsseldorf mds open access latest open access articles published in leukemia s repositioning of quinacrine for treatment of acute myeloid leukemia – promising synergies and in vivo -dose lenalidomide plus cytarabine in very elderly, unfit acute myeloid leukemia patients: final result of a phase ii treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion n partner journal is now partnering with heliyon, an open access journal from elsevier publishing quality peer reviewed research across all disciplines. Partner journals provide authors with an easy route to transfer their research to nging cd30+ es in leukemia and lymphoma resource ing the latest research on leukemia and l issues published in leukemia cts of the vith international eurasian hematology cts of the 12th international symposium on myelodysplastic syndromes (mds). Characterization of two novel fancg mutations in indian fanconi anemia sequencing reveals dnmt3a and asxl1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor therapy.

Exome sequencing reveals dnmt3a and asxl1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor na-181 contributes to downregulation of samhd1 expression in cd4+ t-cells derived from sèzary syndrome patients. Microrna-181 contributes to downregulation of samhd1 expression in cd4+ t-cells derived from sèzary syndrome search returned over 400 essays for "leukemia". Leukemia is a form of cancer that starts in the stem cells of the bone marrow that make blood cells. Leukemia is found in blood cells and since blood cells do not have chromosomes or dna then they cannot divide or reproduce like somatic cells do. Blood cells form in the bone marrow and when too many blood cells form in the human body then leukemia cancer is developed.... Executive summary two promising therapies for leukemia patients are bone marrow transplantation and peripheral stem cell transplantation. In leukemia, the bone marrow produces abnormal white blood cells; these cells crowd out the healthy blood cells, making it hard for blood to do its work ("leukemia," 2013). In fact, it is so common between the ages 0-14, that people refer to it as childhood acute lymphoblastic leukemia (kanwar, 2013). Leukemia leukemia is a cancer that has had a significant effect on our society and with the developments of new drugs it may become treatable. Leukemia originates in the blood-forming organs which may include the lymph tissue and bone cells. In a person with leukemia the rate and the number of cells produced is altered.

People who have leukemia suffer from an abnormal production of white blood cells or known as leukocytes (news,m. Leukemia is defined as the type of cancer in the blood cells that causes the cells to work improperly, usually affecting the white blood cells. Leukemia cancer is a draining disease condition that is heartbreaking to have to watch a family member or friend go through. Medical journal dictionary)leukemia is caused by the rapid production (proliferation) of leukocytes, and causes a build-up that inhibits red blood cells, and platelets from functioning and stops other leukocytes from fighting infection. The literature review was done to gather the information about leukemia therapy within last five years. The information was extracted via pubmed and james white library by inserting the following key terms: leukemia, treatment of leukemia, leukemia and black seeds, chemotherapy for leukemia, nigella sativa, black cumin as anticancer and therapeutic effects of black cumin. As noted in a review of the retrieved articles, different types of medications were used as treatment for leukemia. Many research studies were conducted in order to find a way to limit the progression of leukemia.... Leukemia is cancerous disease that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the blood-stream (national cancer institute, 2008, para. It could be classified as chronic leukemia, which has a slow progress of getting worse or acute leukemia which usually gets worse quickly.... Introduction leukemia and lymphoma society (lls) is the worlds largest non-profit organization which funds blood cancer research and providing patient services and education.

The lls mission is to cure leukemia, lymphoma, hodgkin's lymphoma and myeloma and to improve quality of patients and there families. Over one million americans in the united states are living with or have been diagnosed with leukemia. I chose to do my research paper on leukemia because two years ago i lost my grandma to the cancer. I researched the different types, risk factors, symptoms, treatment, and what kind of research is being done to help cure leukemia. It seems as though there is always something being said about new findings in stem cell research and what will be done with the newly-found information. One of the most conversed aspects of stem cell research is how stem cells can be used to treat potentially life-threatening conditions. Leukemia is one of the conditions being researched along with how stem cell therapy could help benefit the patients with it. In order to fully understand what is going on in the world of stem cell and leukemia research, one must first know what stem cells are and what leukemia is.... Abnormal blood cells produced in the bone marrow develop into a cancerous disease called leukemia. There are various types of leukemia, depending on the type of blood cells involved, and therapy differs for each type. Interferon treatment is not the first line of treatment for leukemia but it helps improve the body's defense against cancer cells, induces remission, and increases survival rates....

Leukemia is a type of cancer that affects the white blood cells in the human body. These cells are known as leukemia cells, which increase in a large mass of number pushing out and destroy the healthy cells. There are several types of leukemia cancers and they are acute lymphocytic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia.... The subject of this paper has been difficult to decide upon until a compelling, entertaining and moving story came to light. In the united states, there was an estimated 310,046 people are living with or are in remission from leukemia according to statistics gathered in 2013. Incidence rates for all types of leukemia developing in males are higher than in females; males are expected to account for approximately 57 percent of the new cases of leukemia. One has to know that leukemia is not just a word, but also a reality. There are many types of leukemia, but there four main types that appear among minors. Through this research, one will discover the different aspects of this cancer and in knowing this may help understand and learn about leukemia more. Childhood leukemia is a blood cancer that begins in early blood-forming cells that are in the bone marrow.... Battling childhood leukemia childhood leukemia is a devastating disease that often leads to death situations.

In knowing the different aspects of this cancer may help understand and learn about leukemia much more. Leukemia is a blood cancer that begins in the bone marrow and white blood cells. The white blood cells help to fight infections in the immune system, but in leukemia, the bone marrow creates abnormal white blood cells.... When a person is diagnosed with acute myeloid leukemia, they will have many good questions. One of the easiest ways to measure the severity of a condition like acute myeloid leukemia is to define it.... General description chronic lymphocytic leukemia (cll) is slow-progressing or “chronic”, cancer of the blood and bone marrow. Cll is the second most common leukemia in adults and one of the four primary types of leukemia. Down’s syndrome is a chromosomal disorder, and acute myeloid leukemia is the most common form of acute leukemia. Large granular lymphocytic (lgl) leukemia is an uncommon disease, characterized by a clonal proliferation of mature, post-thymic t-cells, typically cd3+, cd4-, cd8+, cd16+, cd57+ phenotype, representing constitutively active t-cells less commonly, lgl leukemia is derived from cd3-, cd56+ natural killer (nk) cells. Activating mutations in the stat3gene occur frequently in lgl leukemia, and may play a role in pathogenesis.... There are many discussions that remain in the world about what is the number one killer in children today, cancer; and acute lymphoblastic leukemia is one of the most common childhood diseases, more likely to occur in children under the age of fifteen.

Leukemia-lymphoma) there are few adults that may end up getting acute lymphoblastic leukemia but the symptoms would be much harder to find than it would be in a child. Although cancer in children is getting to the point where it is becoming rare or well it may seem that way, one in every three hundred and fifty american children will start to develop the symptoms of acute lymphoblastic leukemia just by the time they would reach the age of 21... In the paper by fung-lung and colleagues, it was discovered that cd8 is a molecule crucial for the development of cytotoxic t-cells. Leukemia is cancer of the body's blood-forming tissues, such as the bone marrow and the lymphatic system, and causes large amounts of abnormal blood cells to be produced and enter the blood stream (mayo clinic, 2013). Unlike normal blood cells, leukemia cells don’t die when they become old or damaged. Because of this, leukemia cells can build up and crowd out the normal blood cells making it harder for the body to get oxygen to the tissues, control bleeding, or fight infections. Leukemia leukemia is a disease characterized by the formation of abnormal numbers of white blood cells, for which no certain cure has been found. Leukemia is also conditions characterized by the transformation of normal blood-forming cells into abnormal white blood cells whose unrestrained growth overwhelms and replaces normal bone marrow and blood cells. Leukemias are named according to the normal cell from which they originate, such as lymphocyte leukemia. These abnormal cells reproduce in large quantities and look and perform differently than normal cells(medicinenet- leukemia, 1997).... Leukemia leukemia is a group of blood diseases characterized by cancer of the blood forming tissues.

I believe that people do not understand exactly what leukemia is and how dangerous it can be, i chose this topic to try to help them understand. In this paper i will explain what leukemia is and what treatments you can choose from to treat the cancer. Introduction blood cancer is a life-threatening disease that includes: leukemia, lymphoma and myeloma (american society of hematology). Leukemia reduces the ability of white blood cells (wbcs) to fight infection (american society of hematology). In addition, leukemia limits the bone marrow’s ability to produce red blood cells (rbcs) (american society of hematology). Food and drug administration (fda) granted approval to obinutuzumab (previously known as ga101), a cd20-directed cytolytic antibody for use in combination with chlorambucil for treating patients with previously untreated chronic lymphocytic leukemia (cll) (1). A gap in information was also stated as “more research is needed to determine the drivers of higher costs for children who die…targets for cost-saving interventions can be identified (2009). The research article did not clearly state a hypothesis, but it was deduced that the total cost of both the inpatient and outpatient treatment of children with the two cancers identified was going to be very costly. Sample size was clearly identified to the readers as “the final sample consists of 223 children, ages 0-19, who had a first time contact for treatment for leukemia or cns tumor at the clinical site betw... Acute myelogenous leukemia (aml) is a heterogenous disorder characterized by the inhibition of myeloid differentiation in hematopoietic progenitor cells. Introduction acute myeloid leukemia (aml) is a heterogeneous disease characterized by clonal malignant hematopoiesis with a differentiation arrest and excessive proliferation of leukemic blasts.

New drug has potential to destroy leukemia white blood cells are the body's foot soldiers in its everyday battle against infections and diseases. And characterization of somatic mutations associated with progression of acute myeloid leukemia having flt3itd. Fip1l1-pdgfra fusion gene generated by del (4) has also been shown in patients with lymphoblastic leukemias and eosinophilia. There is no such thing as just curiosity, some scientists think these as possibilities to save more human lives and possibly even find a cure for leukemia and cancer, nevertheless, there are people who think these as possibilities towards warfare – as biological weapons.... There is no such thing as just curiosity, some scientists think these as possibilities to save more human lives and possibly even find a cure for leukemia and cancer, nevertheless, there are people that think these as possibilities towards warfare – as biological weapons.... This paper explores the changes in the life of children dealing with cancer, families that have been affected by these diseases (also known as pediatric cancer) and a small part of the journey they experience. This paper investigates the challenges that a family will experience from the first diagnoses through palliative care.... Bone marrow transplants originally developed to allow the use of very high doses of cytotoxic drug treatments for malignancies, such as leukemia (b).... Now, researches have set out to figure out which way is the best for your baby. Conclusion introduction working as a research nurse at the ohio state university, i often encounter patients that are from different cultures. Scientists are attempting to expand on stem cell research, while aspiring towards new medical advancements, but maryland is questioning state-funded research (department of legislative services, office of information systems [dlsois], 2011).

The summer after my freshman year in college, i went back to honduras to volunteer with the children who had leukemia at the national public hospital. The problem is more funding is given to cancer research as opposed to neurological research. Please enable javascript to use all the features on this ia researchvolume 64,   in progressvolume / issue in progressa volume/issue that is "in progress" contains final, fully citable articles that are published online, but the volume/issue itself is awaiting more articles before it can be considered "final". For recently accepted articles, see articles in be assigned a sectioninhibition of sonic hedgehog signaling blocks cell migration and growth but induces apoptosis via suppression of foxq1 in natural killer/t-cell lymphomaoriginal research articlepages 1-9pingyi liu, lingling chenabstractclose research highlights pdf (1248 k). Entitled to full texta phase 1/2 study of rigosertib in patients with myelodysplastic syndromes (mds) and mds progressed to acute myeloid leukemiaoriginal research articlepages 10-16shyamala c. Entitled to full textchk1 inhibitors overcome imatinib resistance in chronic myeloid leukemia cellsoriginal research articlepages 17-23hu lei, jin jin, meng liu, xiangyun li, hao luo, li yang, hanzhang xu, yingli wuabstractclose research highlights pdf (1013 k). This free service is available to anyone who has published and whose publication is in practice & research: clinical y of blood and marrow al lymphoma, myeloma & mental logy/oncology clinics of north ia research rs in leukemia research ly published articles from leukemia chelation therapy in lower ipss risk myelodysplastic syndromes; which subtypes benefit? 1 inhibitors overcome imatinib resistance in chronic myeloid leukemia lei | jin jin | meng liu | xiangyun li | hao luo | li yang | hanzhang xu | yingli wu. Tion of sonic hedgehog signaling blocks cell migration and growth but induces apoptosis via suppression of foxq1 in natural killer/t-cell liu | lingling side a potentiates the effects of conventional therapeutic agents in acute leukemia. Rivera-franco | diana gómez-martín | jorge romo-tena | guillermo juárez-vega | javier merayo-chalico | jorge tors for requiring re-induction chemotherapy in acute myeloid leukemia patients with residual disease on day 14 bone marrow ia r. Bove | gabriela sanchez-petitto | srdan 1 gene and mirna dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic ozdogan | bala gur dedeoglu | yasemin oztemur islakoglu | alp aydos | sevil kose | arzu atalay | zeynep arzu yegin | ferit avcu | duygu ocean cetinkaya | osman al and biological significance of isolated y chromosome loss in myelodysplastic syndromes and chronic myelomonocytic leukemia.

A report from the spanish mds ell nomdedeu | arturo pereira | xavier calvo | joan colomer | francesc sole | amparo arias | candida gomez | elisa luño | jose cervera | montserrat arnan | helena pomares | fernando ramos | itziar oiartzabal | blanca espinet | carme pedro | beatriz arrizabalaga | maría laura blanco | mar tormo | jesus maria hernandez-rivas | maría díez-campelo | margarita ortega | david valcárcel | maria-teresa cedena | rosa collado | javier grau | isabel granada | guillermo sanz | elias campo | jordi esteve | dolors s repositioning of quinacrine for treatment of acute myeloid leukemia – promising synergies and in vivo eriksson | efthymia chantzi | mårten fryknäs | joachim gullbo | peter nygren | mats gustafsson | martin höglund | rolf prognostic value of pre-allogeneic stem cell transplantation minimal residual disease detection by wt1 gene expression in aml transplanted in cytologic complete candoni | federico de marchi | maria elena zannier | davide lazzarotto | carla filì | maria vittoria dubbini | nicholas rabassi | eleonora toffoletti | bonnie w. Sekeres | thomas prebet | thomas cluzeau | valeria santini | emmanuel gyan | alessandro sanna | najla hal ali | sean hobson | virginie eclache | alan list | pierre fenaux | lionel adèct ephb4-mediated mechanisms of apoptotic and resistance to dasatinib in human chronic myeloid leukemia and k562 cell -hong zhao | bin-tao huang | jian-yu zhang | qing-chun stemin silencing induces differentiation and potentiates all-trans-retinoic acid effects in human acute promyelocytic leukemia nb4 cells via fakhimahmadi | farinaz nazmi | marveh rahmati | nazila moghtaran bonab | mehrdad hashemi | mohammad amin onship between lenalidomide dose modification, duration of therapy, and long-term outcomes in patients with myelodysplastic e. Vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: a pilot ble online 11 november t. Nate induces apoptosis via inhibition of stat3 in thp-1 tan | ying rong | qiong su | yan in vivo anti-leukemia activity of n-(1-pyrenlyl) maleimide in a bioluminescent mouse -yuan chen | pei-chi chang | tong-hong wang | tzu-chien v. Dose lenalidomide plus cytarabine in very elderly, unfit acute myeloid leukemia patients: final result of a phase ii pe visani | felicetto ferrara | francesco di raimondo | federica loscocco | fabio fuligni | stefania paolini | valentina zammit | eleonora spina | marco rocchi | axel visani | pier paolo piccaluga | alessandro -effectiveness of methods in personalized medicine. Results of a decision-analytic model in patients with acute myeloid leukemia with normal hörster | richard f. Schlenk | michael stadler | maria gabriel | felicitas thol | jan schildmann | jochen vollmann | ursula rochau | gaby sroczynski | jürgen wasem | arnold ganser | matthias port | anja c variations of bone marrow mesenchymal stromal cells derived from acute leukemia and myelodysplastic syndrome by targeted deep azuma | tomohiro umezu | satoshi imanishi | michiyo asano | seiichiro yoshizawa | seiichiro katagiri | kazuma ohyashiki | junko h. Of bix-01294 on proliferation, apoptosis and histone methylation of acute t lymphoblastic leukemia huang | yong zou | luhui lin | xudong ma | xiaohong s of arsenic disulfide on apoptosis, histone acetylation, toll like receptor 2 activation, and erythropoiesis in bone marrow mononuclear cells of myelodysplastic syndromes patients in xu | jian-ye ren | yuan-cheng guo | bai-xue xu | qing zeng | qi hu | yong-ming zhou | jia-hui omib in plasmablastic lymphoma: a glimpse of hope for a hard-to-treat a. Mendler | debra masel | jane liesveld | christopher aquina | neil riptome analysis of cd34+ cells from myelodysplastic syndrome g ou | jing huang | huijuan shen | zhi liu | yangmin zhu | qi zhong | liling zheng | mengdong yao | yanling she | shanyao zhou | rui chen | cheng li | qing zhang | shuang er of multidrug resistance among acute myeloid leukemia cells via extracellular vesicles and their microrna cargo. And changes in code status of patients with acute myeloid leukemia undergoing induction chemotherapy who were transferred to the intensive care d ahmed | abby l. Douglas -remissional and pre-transplant role of minimal residual disease detected by wt1 in acute myeloid leukemia: a retrospective cohort frairia | semra aydin | ernesta audisio | ludovica riera | sabrina aliberti | bernardino allione | alessandro busca | stefano d'ardia | chiara maria dellacasa | anna demurtas | andrea evangelista | giovannino ciccone | paola francia di celle | barbara nicolino | alessandra stacchini | filippo marmont | umberto tory macrocytic anemias in patients with clonal hematopoietic disorders and isolated mutations of the spliceosome gene a.

1 synergizes with flt3 ligand to induce chemoresistant quiescence in acute lymphoblastic leukemia with mll gene rearrangements.